[84718-95-6]    

Synonyms : 1,3-Dimethyl-1H-purine-2,6(3H,7H)-dione-1,3-15N2-2-13C; 1,3-Dimethylxanthine-1,3-15N2-2-13C

Applications : Theophylline-1,3-15N2-2-13C is the mixed labelled analog of Theophylline, which is a nonselective phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator; used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma.

References : Deree J. et al. Clinics (Sao Paulo) 63(3), 321-328, 2008; Marques L. J. et al.: Am J. Respir Crit Care Med., 159(2), 508-511, 1999; Daly J. W.: et al. Prog Clin Biol Res., 230, 41-63, 1987.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.