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SL-5007

Ambrisentan impurity E, >98%

CAS No. : 
[1312092-82-2]    
Synonyms : 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3,3-diphenylacrylic acid

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG120.00
-
+
Back Order Estimated to Ship on 12.15.2024
100MG980.00
-
+
Back Order Estimated to Ship on 12.15.2024
Chemical Properties
C21H18N2O3 346.39
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : This is an impurity of Entacapone (Ambrisentan impurity E), which is an inhibitor of catechol-O-methyltransferase (COMT), used in the treatment of parkinson's disease as an adjunct to levodopa and carbidopa therapy.
References : Weiss J. et al.: Eur J Pharmacol, 660(2-3), 298-304, 2011; Yokoyama Y. et al.: Biol Pharm Bull, 37(3), 461-465, 2014; Weiss J. et al.: Biochem Pharmacol, 85(2), 265-273, 2013; Osano A. et al.: J. Pharmacol Sci, 124(1), 86-91, 2014; Buckley M. S. et al.: Expert Opin Drug Metab Toxicol, 7(3), 371-380, 2011.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-5007

Product Name : Ambrisentan impurity E

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