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SL-6474

3-Dechloro-3-bromo roflumilast, >98%

Synonyms : N-(3-Bromo-5-chloropyridin-4-yl)-3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamide

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG180.00 Back Order Estimated to Ship on 12.18.2024
100MG1280.00 Back Order Estimated to Ship on 12.18.2024
Chemical Properties
C17H14BrClF2N2O3 447.66
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : This is an impurity of Roflumilast, which is a selective phosphodiesterase-4 (PDE-4) inhibitor, used in the treatment of severe chronic obstructive pulmonary disease (COPD).
References : Hatzelmann A. et al.: Pulm Pharmacol Ther., 23 (4), 235-256, 2010; Rabe K. F. Br. J. Pharmacol., 163 (1), 53-67, 2011; Hatzelmann A. et al.: J. Pharmacol Exp Ther., 297 (1), 267-279, 2001; Richmond B. W. et al.: Nat. Commun. 7, 11240, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-6474

Product Name : 3-Dechloro-3-bromo roflumilast

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