SynInnova Laboratories Inc.

SL-7126

Afatinib impurity C, >98%

CAS No. :

[945553-91-3]

MDL No. :

MFCD18711941

Synonyms : (R,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide; (R)-Afatinib

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	150.00	- +	Back Order	Estimated to Ship on 01.20.2025
10MG	280.00	- +	Back Order	Estimated to Ship on 01.20.2025
25MG	650.00	- +	Back Order	Estimated to Ship on 01.20.2025
50MG	1150.00	- +	Back Order	Estimated to Ship on 01.20.2025

Chemical Properties
Mol. Formula : C₂₄H₂₅ClFN₅O₃	Mol. Weight : 485.94
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an opposite enantiomer and an impurity of Afatinib (Afatinib impurity C), which is an irreversible EGFR family inhibitor, used to treat metastatic non-small cell lung cancer (NSCLC).

References : Li D. et al.: Oncogene, 27(34), 4702-4711, 2008; Ferrarotto R. et al.: Expert Opin Investig Drugs, 23(1), 135-43, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-7126

Product Name : Afatinib impurity C

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SL-7142	Afatinib impurity 8
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SL-7139	Afatinib impurity 5
SI-3912	7-Chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine
SL-7131	Afatinib impurity H
SL-7147	Afatinib impurity 13
SL-7153	Afatinib impurity 19
SL-7154	Afatinib impurity 20
SI-2480	Afatinib
SL-7132	Afatinib impurity I
SL-7128	Afatinib impurity E

SL-2164	Omeprazole-d₃ sulfide
SL-7126	Afatinib impurity C
SL-2182	4-Desmethoxy-4-nitro omeprazole sulfide
SL-2130	(S)-Doxazosin-d₈
SL-2189	5-O-Desmethyl omeprazole
SL-2171	Omeprazole-d₃ acid disodium salt
SL-2169	Omeprazole-d₃ acid methyl ester sulfide
SL-3525	Macitentan impurity 7
SL-3572	Mycophenolate mofetil N-oxide
SL-2183	4-Desmethoxy omeprazole
SL-2160	Omeprazole sulfone
SL-2154	Omeprazole-13C, d3

SL-7126

Afatinib impurity C, >98%

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