SynInnova Laboratories Inc.

SL-7146

Afatinib impurity 12, >98%

CAS No. :

[2121530-37-6]

Synonyms : (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-hydroxybut-2-enamide

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	680.00	- +	In Stock	Estimated to Ship on 12.06.2024
10MG	1280.00	- +	In Stock	Estimated to Ship on 12.06.2024

Chemical Properties
Mol. Formula : C₂₂H₂₀ClFN₄O₄	Mol. Weight : 458.87
Appearance : Pale yellow solid	Melting Point : Not available
Solubility : DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Afatinib (Afatinib impurity 12), which is an irreversible EGFR family inhibitor, used to treat metastatic non-small cell lung cancer (NSCLC).

References : Li D. et al.: Oncogene, 27(34), 4702-4711, 2008; Ferrarotto R. et al.: Expert Opin Investig Drugs, 23(1), 135-43, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-7146

Product Name : Afatinib impurity 12

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