SynInnova Laboratories Inc.

SL-7478

MDL-28170, >98%

CAS No. :

[88191-84-8]

MDL No. :

MFCD29055381

Synonyms : Benzyl ((S)-3-methyl-1-oxo-1-(((S)-1-oxo-3-phenylpropan-2-yl)amino)butan-2-yl)carbamate; MDL28170

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
50MG	180.00	- +	Back Order	Estimated to Ship on 12.22.2024
500MG	1580.00	- +	Back Order	Estimated to Ship on 12.22.2024

Chemical Properties
Mol. Formula : C₂₂H₂₆N₂O₄	Mol. Weight : 382.46
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : MDL-28170 is a potent, selective and membrane-permeable cysteine protease inhibitor of calpain that rapidly penetrates the blood-brain barrier following systemic administration. MDL-28170 also block γ-secretase. Also, a novel therapeutic option for targeting SARS-CoV entry (EC50=100 nM). A useful COVID-19 research chemical.

References : Chen Z. F. et al.: Brain Res., 769(1), 188-92, 1997; Li P. A. et al.: Neurosci Lett., 247(1), 17-20, 1998; Ai J. et al.: J. Neurotrauma., 24(6), 960-78, 2007; De Strooper B. et al.: Nature 398(6727) 518-22, 1999; Kharatmal S. B. et al.: Neuropharmacology 97, 113-21, 2015. A. Zumla A. et al.: Nat. Rev. Drug. Discov.,15, 327-347, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-7478

Product Name : MDL-28170

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