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SI-5129

Sivelestat sodium, >98% (HPLC)

CAS No. : 
[150374-95-1]    
MDL No. : 
MFCD08461731
Synonyms : Sodium (2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycinate; LY-544349 sodium; ONO-5046 sodium; EI-546 sodium

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG120.00 Back Order Estimated to Ship on 12.12.2024
25MG280.00 Back Order Estimated to Ship on 12.12.2024
50MG550.00 Back Order Estimated to Ship on 12.12.2024
100MG1050.00 Back Order Estimated to Ship on 12.12.2024
250MG2250.00 Back Order Estimated to Ship on 12.12.2024
Chemical Properties
C20H21N2NaO7S 456.44
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat sodium has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
References : Kawabata K. et al.: Biochem Biophys Res Commun., 177(2), 814-20, 1991; Toda Y. et al.: Int. J. Mol Med., 19(2), 237-43, 2007; Kono T. et al.: Mol Cell Biochem., 311(1-2), 87-92, 2008; Sahebnasagh A. et al.: J. Clin Pharm Ther., 45(6), 1515-1519, 2020.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5129

Product Name : Sivelestat sodium

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