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SI-3489

Ceritinib dihydrochloride, >98% (HPLC)

CAS No. : 
[1380575-43-8]    
MDL No. : 
MFCD26142928
Synonyms : 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine dihydrochloride; LDK378 dihydrochloride

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MGRequest QuoteBack Order Estimated to Ship on 01.25.2025
25MGRequest QuoteBack Order Estimated to Ship on 01.25.2025
100MGRequest QuoteBack Order Estimated to Ship on 01.25.2025
Chemical Properties
C28H36ClN5O3S . 2HCl 631.05
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Ceritinib dihydrochloride is a potent inhibitor against ALK with IC50 of 0.2 nM in cell-free assays, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.
References : Flick C. A et al.: Bioorg. Med. Chem. 24(9), 1937-1980, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-3489

Product Name : Ceritinib dihydrochloride

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