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SI-5011

Desmethyl cariprazine, >98% (HPLC)

CAS No. : 
[839712-15-1]    
Synonyms : 1-((1r,4r)-4-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)-3-methylurea

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG280.00 Back Order Estimated to Ship on 12.25.2024
10MG500.00 Back Order Estimated to Ship on 12.25.2024
25MG1100.00 Back Order Estimated to Ship on 12.25.2024
Chemical Properties
C20H30Cl2N4O 413.39
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Desmethyl cariprazine is an active metabolite of Cariprazine. Cariprazine, an antipsychotic drug candidate, exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).
References : Seneca N. et al.: Psychopharmacology (Berl). 218 (3), 579, 2011; Kiss B. et al. J Pharmacol Exp Ther. 333 (1), 328-340, 2010; Zimnisky R. et al.: Psychopharmacology (Berl). 226 (1), 91-100, 2013; Gao Y. et al.: Pharmacol Res Perspect., 3(1), e00073, 2015.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5011

Product Name : Desmethyl cariprazine

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