SynInnova Laboratories Inc.

SI-5739

Durlobactam, >98% (HPLC)

CAS No. :

[1467829-71-5]

Synonyms : (2S,5R)-2-Carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl hydrogen sulfate; ETX-2514

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 02.15.2025
25MG	Request Quote	- +	Back Order	Estimated to Ship on 02.15.2025
100MG	Request Quote	- +	Back Order	Estimated to Ship on 02.15.2025
250MG	Request Quote	- +	Back Order	Estimated to Ship on 02.15.2025
500MG	Request Quote	- +	Back Order	Estimated to Ship on 02.15.2025

Note: Durlobactam is not in stock, can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
Mol. Formula : C₈H₁₁N₃O₆S	Mol. Weight : 277.25
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Durlobactam is a β-lactamase inhibitor drug candidate. Sulbactam-durlobactam (formerly sulbactam-ETX2514) (SUL-DUR) is a β-lactam/β-lactamase inhibitor combination antibiotic designed to treat serious infections caused by ABC, including multidrug-resistant (MDR) strains. SUL-DUR had a MIC50/MIC90 of 1/2 μg/ml compared to a MIC50/MIC90 of 8/64 μg/ml for sulbactam alone.

References : Rodvold K. A. et al.: Antimicrob Agents Chemother., pii: AAC.01089-18, 2020; Iyer R. et al.: ACS Infect Dis., 4(3), 373-381, 2018; McLeod S. M. et al.: Antimicrob Agents Chemother., 62(2). pii: e01576-17, 2018; Shapiro A. B. et al.: ACS Infect Dis., 3(11), 833-844, 2017; Durand-Reville T. F. et al.: Nat Microbiol., 2, 17104, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

To receive price and delivery information on larger quantities, please complete the form below and we will respond promptly.

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Your request for quote will also be accepted by e-mail at sales@syninnova.com or Fax: +1 780 485 2963.

Product ID : SI-5739

Product Name : Durlobactam

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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SI-5739

Durlobactam, >98% (HPLC)

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