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SL-3358

N6-(2-Carboxyethyl) ibrutinib, 98%

Synonyms : (R)-3-((1-(1-Acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)propanoic acid

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG160.00 Back Order Estimated to Ship on 12.23.2024
10MG300.00 Back Order Estimated to Ship on 12.23.2024
25MG750.00 Back Order Estimated to Ship on 12.23.2024
Chemical Properties
C28H28N6O4 512.56
Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : N6-(2-Carboxyethyl) ibrutinib is an impurity of Ibrutinib, which is a selective, irreversible Bruton's tyrosine kinase (Btk) inhibitor, used to treat B cell cancers like mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström's macroglobulinemia.
References : Honigberg L. A. et al.: Proc. Nat. Acad. Sci., U S A. 107 (29),13075-13080, 2010; Herman S.E. et al.: Blood. 117 (23), 6287-6296, 2011; Chang B.Y. et al.: Arthritis Res Ther., 13(4), R115, 2011; Wu H. et al.: Sci Rep., 7 (1), 466, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3358

Product Name : N6-(2-Carboxyethyl) ibrutinib

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