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SL-4989 

(R)-Ambrisentan, >98%

CAS No. : 
[1007358-76-0]    
Synonyms : (R)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG580.00
-
+
In Stock Estimated to Ship on 12.01.2024
100MG980.00
-
+
In Stock Estimated to Ship on 12.01.2024
Chemical Properties
C22H22N2O4 378.43
White to Off-white solid Not available
DMSO
For Laboratory research use only, not for drug, household or other uses.
Applications : (R)-Ambrisentan is an (R)-isomer of Ambrisentan. A highly selective antagonist of the endothelin-1 type A receptor (ETAR), used in the treatment of pulmonary arterial hypertension (PAH).
References : Weiss J. et al.: Eur J Pharmacol, 660(2-3), 298-304, 2011; Yokoyama Y. et al.: Biol Pharm Bull, 37(3), 461-465, 2014; Weiss J. et al.: Biochem Pharmacol, 85(2), 265-273, 2013; Osano A. et al.: J. Pharmacol Sci, 124(1), 86-91, 2014; Buckley M. S. et al.: Expert Opin Drug Metab Toxicol, 7(3), 371-380, 2011.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-4989

Product Name : (R)-Ambrisentan

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