Get in Touch



SL-5002

Ambrisentan N-oxide, >98%

Synonyms : (S)-2-(1-Carboxy-2-methoxy-2,2-diphenylethoxy)-4,6-dimethylpyrimidine 1-oxide

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG680.00 Back Order Estimated to Ship on 01.20.2025
10MG1280.00 Back Order Estimated to Ship on 01.20.2025
Chemical Properties
C22H22N2O5 394.43
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : This is an oxidative metabolite of Ambrisentan, which is a highly selective antagonist of the endothelin-1 type A receptor (ETAR), used in the treatment of pulmonary arterial hypertension (PAH).
References : Weiss J. et al.: Eur J Pharmacol, 660(2-3), 298-304, 2011; Yokoyama Y. et al.: Biol Pharm Bull, 37(3), 461-465, 2014; Weiss J. et al.: Biochem Pharmacol, 85(2), 265-273, 2013; Osano A. et al.: J. Pharmacol Sci, 124(1), 86-91, 2014; Buckley M. S. et al.: Expert Opin Drug Metab Toxicol, 7(3), 371-380, 2011.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

To receive price and delivery information on larger quantities, please complete the form below and we will respond promptly.

If you login prior to completion of the form, your contact information will automatically populate.

Your request for quote will also be accepted by e-mail at sales@syninnova.com or Fax: +1 780 485 2963.

Product ID : SL-5002

Product Name : Ambrisentan N-oxide

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!