SynInnova Laboratories Inc.

SI-5728

PR-924, >98% (HPLC)

CAS No. :

[1416709-79-9]

Synonyms : N-((R)-1-(((S)-3-(1H-Indol-3-yl)-1-(((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)-3-methyl-1H-indene-2-carboxamide

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
25MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
100MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
250MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
500MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025

Note: PR-924 is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
Mol. Formula : C₃₇H₃₈N₄O₅	Mol. Weight : 618.73
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PR-924 is a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor with an IC50 of 22 nM. PR-924 covalently modifies proteasomal N-terminal threonine active sites. PR-924 inhibits growth and triggers apoptosis in multiple myeloma (MM) cells. PR-924 has antitumor activities.

References : Singh A. V. et al.: Br. J. Haematol., 152(2), 155-63, 2011; Parlati F. et al.: Blood 114(16), 3439-47, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5728

Product Name : PR-924

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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SI-5728

PR-924, >98% (HPLC)

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